A simple go-or-grow model of aerotaxis along a self-generated gradient

Vincent Calvez (UCB Lyon)

Nov 21. 2022, 14:15 — 15:00

I will report on a minimal model introduced to describe expansion of a cell colony (Dictyostelium discoideum) in response to aerotaxis. The model is essentially based on the hypothesis that cells may either divide if oxygen is available in a sufficient amount, or move directionaly along its gradient if oxygen concentration is too low. Interestingly, the speed of expansion is explicit, and it reveals a transition between pulled and pushed fronts. This enables discussing the relative importance of the three parameters in the model (rate of division, averaged speed of directional motion, and cell diffusion coefficient) to the dynamics of expansion.  

Further Information
ESI Boltzmann Lecture Hall
Associated Event:
Mathematical Methods for the Study of Self-organization in the Biological Sciences (Thematic Programme)
Pierre Degond (IMT)
Marie Doumic (Sorbonne U, Paris)
Anna Kicheva (ISTA, Klosterneuburg)
Sara Merino-Aceituno (U of Vienna)
Christian Schmeiser (U of Vienna)